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Boron containing compounds have not been widely studied in Medicinal Chemistry, mainly due to the idea that this group could confer some toxicity. Nowadays, this concept has been demystified and, especially after the。

Boronic acids are increasingly boronicutilised in diverse areas of research. Including the interactions of boronic acids with diols and strong Lewis bases。

Optimizing the compatibility of boronic acids for MCR is an intereboronicsting synthetic challenge, as the C─B bond is well known to react with common MCR starting materials and intermediates under mild conditions,。

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